By Greg Seigle
Global Security Newswire
While the $3 billion biodefense authorization bill currently under scrutiny in the U.S. Senate appears poised to pass soon and distribute $1 billion across all 54 U.S. states and territories next year—dwarfing the $10 million the White House initially proposed—state and local medical communities could still experience dangerous budget shortfalls in their efforts to prepare for nightmare scenarios, analysts said.
“If we spend less than $2 billion [next] year on local, state [and] city health departments, then our leaders don’t know what’s going on and don’t get it,” Tara O’Toole, director of the Johns Hopkins University Center for Civilian Biodefense Studies, said during a recent speech.
“Some of that money is going to waste. There’s no help for that,” added O’Toole, who served as assistant secretary of energy for environmental safety and health during the Clinton administration. “We have got to get money to the local level very quickly in order to just get some raw capacity in there.”
Roughly two-thirds of the $3 billion offered in the bipartisan bill is slated for federal coffers, much of it earmarked to develop, purchase and stockpile smallpox vaccines (see GSN, Nov. 29). A similar bill being formulated in the House is expected to make similar recommendations, according to congressional staffers (see GSN, Dec. 11).
While the boosting of vaccine stockpiles is sorely needed—including vaccines for biological agents other than smallpox—a national bioterrorism response strategy should give equal weight to preparing local medical authorities, sources said. It is these people who will be on the front lines should biological weapons ever be unleashed by terrorists.
The Senate bill, introduced by Senators Bill Frist (R-Tenn.) and Ted Kennedy (D-Mass.) (see GSN, Nov. 15), initially sought to provide $5 billion—a large chunk of which was aimed at providing resources to the states and local governments. But Bush administration officials have vowed to veto any bills that surpass the $686 billion budget for 2002—or the $40 billion already designated for terrorism response.
“If we invested the kind of monies now that we did when [the Soviet satellite] Sputnik went up [and led to the creation of the] Apollo project, I think we would not only remove biological weapons as weapons of mass destruction threats, but I think we would also give the world great aid in dealing with malaria, [tuberculosis] and AIDS,” O’Toole said.
“It’s not a matter of [states receiving] $1 billion or $2 billion, it’s a matter of slowly building up your capabilities,” said Jonathan Ban, a research associate with the Chemical and Biological Arms Control Institute. “You do need a smallpox vaccine and you do need vaccines for all the other [diseases], even though you might not use them. But you can’t do it at the expense of state and local resources because you’re definitely going to use them.”
A “System of Systems” Needed
“You can have all the stockpiles of vaccines you want but if you don’t have a system in place to distribute them there’s going to be hell to pay,” Ban said.
“You have to have a system of systems to combat bioterrorism” at the vital local level, Ban said. “You need a system that has detection capabilities, laboratory diagnostics, epidemiological capabilities … Currently there isn’t any of that.”
Ban served as the lead analyst for the U.S. Centers for Disease Control and Prevention report “Bioterrorism in the United States,” released in July after a 15-month study that examined the response capabilities of seven large cities, including New York, which is considered the leader in civilian biological defense preparedness.
In the last couple years New York has established an evolving monitoring system that enables local authorities to track and categorize hospital admissions, 911 calls, water supplies and even absenteeism rates with large employers. If authorities notice a spike in one or more of the categories they might be able to head off a biological outbreak before it spreads too fast, sources said.
Quick Response is Key
“If you don’t detect [a biological attack] early it’s going to be a big problem, the way people move around [the world] today,” Ban said. “The better you respond, the better you can handle the situation and mitigate the consequences.”
Currently the CDC advocates a “ring containment” strategy (see GSN, Nov. 27) modeled after the World Health Organization method that successfully eradicated smallpox from the world by 1980. If one person is exposed to a contagious, potentially lethal biological agent, local authorities need to quarantine them quickly and at least the last 20 people who had been in contact with them. Sources said the crucial factor in such worrisome scenarios is rapidly identifying the outbreak, so it can be contained. Hence, doctors, emergency crews and other local officials on the front lines need to have as much funding as training as possible, they said.
“I think it’s pretty apparent to people by now, following the anthrax attacks, that medicine and public health is at the heart of a response to bioweapons threats,” said O’Toole.
Public Health Vulnerabilities
“There are a lot of vulnerabilities” at the local level, she said. “First of all, [doctors] haven’t seen anthrax. They haven’t seen smallpox. They don’t know what to look for. They don’t know how to diagnose it. The big problem we saw [was] with the two patients, one in D.C. and one in Maryland who went to their doctor’s offices, went to the emergency room and were sent home with anthrax and later tragically died.”
In addition, there is no surge capability in the medical system, sources said. Hospitals keep just enough supplies and workforce on hand for daily needs—and they are pitted against each other as competitors and not prepared to work together, sources added.
“In the search for [financial] efficiency we have eliminated all excess capability,” said O’Toole. “The public health system is even worse shape … We have not invested sufficiently in this system … The local health departments are bereft of resources. Half of them do not have Internet connections.”
“Connectivity is a major problem,” Ban added. “Hospitals are unprepared, doctors are unaware … Many of the locales don’t even have distribution systems.”
In the event of a biological attack, CDC plans call for federal authorities to fly in vaccines and other emergency supplies and drop off them at a prearranged airport hangar, sources said. Then it is up to local officials to distribute these crucial supplies.
One big-city fire chief interviewed by Ban for the CDC study said he planned to take the vaccines and other supplies to fire stations, then go on local television to inform the public to come get their shots.
“Can you imagine the psychological effect, the mad runs on the fire house?” Ban asked. “And would the fire chief himself be the one administering antibiotics?”
The spores used in the U.S. anthrax incidents match those recently produced by the U.S. military for investigative purposes, the Baltimore Sun reported today. As the “Amerithrax” investigation continues, however, critics are questioning theories that point to a U.S. military connection, according to reports.
Scientists at the Dugway Proving Ground in Utah have produced small amounts of weapon-grade anthrax that is nearly identical to the spores used in the incidents, U.S. sources said. The production of weaponized anthrax is apparently the first since former U.S. President Richard Nixon ended the U.S. offensive biological weapons program in 1969, the Sun reported.
Dugway researchers sent the newly produced anthrax—via Federal Express—to the U.S. Army Military Institute of Infectious Diseases (USAMIID) for sterilization. USAMIID shipped the spores back to Dugway as a coarse paste, according to the Sun. Dugway researchers then used the killed spores to minimize risks to workers while conducting experiments. Some experiments, such as those on decontamination methods and detection systems, needed to use live and weaponized anthrax, according to government sources.
Army officials said the anthrax stored at Dugway and USAMIID were protected by several security measures. At Dugway, security measures included video cameras, intrusion alarms and a “buddy system,” which does not allow researchers to handle anthrax and other microbes alone, according to one scientist.
Dugway produced the live anthrax because vaccines and other preventive measures need to be tested against aerosolized anthrax, according to David Huxsoll, a former head of the USAMIID’s biodefense program. “When you’re building a program to defend against biological weapons on the battlefield, you have to be prepared for an aerosol exposure,” Huxsoll said.
The Army’s production of small amounts of weapon-grade anthrax at Dugway would not violate the Biological Weapons Convention, said University of Maryland expert Milton Leitenberg. The convention only bans the production of biological warfare agents for non-protective measures. “There’s no specific limit in grams or micrograms,” Leitenberg said. “But if you got up in the hundreds of grams, people would be very, very skeptical” (Scott Shane, Baltimore Sun, Dec. 12).
Rosenberg Theory Questioned
A recent report that suggests someone connected to the U.S. military is responsible for the anthrax incidents has several inaccuracies that call its conclusions into question, according to the New Republic (see GSN, Dec. 4).
One false conclusion made in the report, prepared by Barbara Hatch Rosenberg, head of the Federation of American Scientists’ Working Group on Biological Weapons Verification, is that the limited circle of research facilities with access to the Ames strain of anthrax—the same strain used in the incidents—suggests a domestic source, the New Republic reported.
Terrorists could just as easily obtain Ames strain spores from a recently dead cow, according to David Huxsoll, interim director of the Plum Island Animal Disease Center in New York. The Ames strain, which was first isolated in 1929, is a monomorphic disease—one in which strains mutate slowly, or not at all—Huxsoll said. Spores taken from a cow that died recently would be virtually the same as the Ames strain used by researchers, he said.
“One should not be at all surprised that you could find something very much the same—it would be a surprise to find something very different,” said Huxsoll. “If I were a terrorist, I’d just go where the disease occurs naturally and dig it up.”
The Rosenberg report also said the United States first researched a strain of anthrax called Vollum 1B as a weapon (see GSN, Dec. 10), but then “the search undoubtedly continued for better strains. The U.S. bioweapons program apparently switched to the Ames reference strain because of its high virulence.”
There is no evidence of such a switch in research having taken place, according to the New Republic. The U.S. biological weapons program never gave up working with Vollum 1B, according to a law-enforcement official. Instead, when researchers saw how slowly anthrax killed its victims, they abandoned work on it altogether, the New Republic reported. “Who the hell wanted a weapon that would take 60 days to kill?” asked the official.
If any former employees of the U.S. biological warfare program kept supplies of old anthrax, they would be Vollum 1B spores, not Ames, according to the New Republic. There is no evidence the United States has produced weaponized Ames strain anthrax, the New Republic reported.
Rosenberg also wrote in her report that “The extraordinary concentration (one trillion spores per gram) and purity of the letter anthrax is believed to be characteristic of material made by the U.S. process.” This does not mean, however, that other countries could not produce anthrax of similar quality, according to the New Republic.
The former Soviet biological weapons program deliberately used anthrax powder that consisted of only 25 percent anthrax by weight, according to Ken Alibek, former deputy director of the Soviet biological weapons program. This was done not because the Soviets could not produce better quality anthrax, but because more concentrated anthrax was unnecessary for use in a missile weapon, the New Republic reported.
“I still don't see any geography here ... we are not going to find a smoking gun,” said former USAMIID commander David Franz. “The anthrax could have been made in any place at any time. We have to get away from the idea that you can just analyze these samples and tell who made them” (Wendy Orent, New Republic, Dec. 11).
University Inspections Begin
Research facility inspections began yesterday at the University of Texas Medical Branch at Galveston (see GSN, Dec. 10), a university official said. Investigators from the U.S. Health and Human Services Department’s Office of the Inspector General are examining the security of biological samples and computer data, said university spokesman Tom Curtis. The investigation could last up to four weeks, Curtis said. “It amounts to an audit.”
The university is fully cooperating with the investigation, Curtis said. “I don’t question the need for someone to look into dangerous materials and make sure they are being handled appropriately” (CNN.com, Dec. 12).
Information Needs to be Shared
New York Police Commissioner Bernard Kerik yesterday asked the U.S. Senate to pass proposed legislation that would make it easier for local law enforcement to obtain information from the FBI. The walls between the two agencies were “the worst kind of dysfunctional thinking in government,” Kerik said.
In testimony before the Senate Judiciary Subcommittee on Administrative Oversight in the Courts, Kerik discussed the anthrax incident involving a suspicious letter sent to NBC’s studios on Oct. 12. New York police did not learn about that letter until almost a week after the FBI had been notified, Kerik said.
That example showed the need for better communication between local and federal law enforcement, according to Kerik. “We could have been on the issue instantly,” Kerik said. “And that sort of brought all of this to light. The FBI had not let us know.”
The proposed legislation, sponsored by Senators Charles Schumer (D-N.Y.) and Hillary Clinton (D-N.Y.), would allow federal authorities to share information gathered from sources such as wiretaps, grand juries and foreign intelligence operations with local law enforcement officials. The new bill, however, would not require federal law enforcement to do so.
Witnesses at the hearing said that while the legislation would not eliminate the withholding of information between federal and local law enforcement, it would remove an oft-cited reason federal law enforcement uses to do so.
“It’s possible that countless New Yorkers were unnecessarily put at risk simply because the law and culture makes information-sharing taboo,” said Subcommittee Chairman Schumer. “That’s a risk that none of us should ever be forced to take” (Raymond Hernandez, New York Times, Dec. 12).
Canadians Knew of Anthrax Letter Dangers
Canadian military officials knew several months before the U.S. anthrax incidents that letters filled with anthrax spores posed a risk to mail handlers and that opening a tainted letter could send spores into the air, according to the Wall Street Journal.
A Canadian study was discussed yesterday at a meeting called by the U.S. Centers for Disease Control and Prevention regarding the anthrax incidents. Canadian officials said they had e-mailed the study to the CDC soon after reports of the discovery of anthrax at the American Media Inc. headquarters in Florida. The e-mail, however, was never opened, said Bradley Perkins, a CDC anthrax investigator.
Perkins said he regretted that the report was not read. “It is certainly relevant data, but I don’t think it would have altered the decisions that we made,” Perkins said (Chad Terhune, Wall Street Journal, Dec. 12).
Organizers of the CDC meeting also asked participants to come up with the answers to several research questions concerning anthrax, according to the New York Times. The questions included the following:
* What is the minimum number of spores needed to infect a human (see GSN, Nov.16)?
* How long do exposed people need to take antibiotics?
* When is a decontaminated office or building safe?
“We wish we had the answers today,” said James Hughes, the CDC official overseeing the anthrax investigation (Lawrence Altman, New York Times, Dec. 12).
Hart Building Cleanup Continues
Small items, such as files, computers and books, which may have been tainted with anthrax inside the Hart Senate Office Building, will be shipped to Richmond, Va., for further decontamination, officials said yesterday.
The items have been fumigated once during the decontamination of the entire building, but this move is an extra dose of caution, officials said (see GSN, Dec. 4). The process, which uses ethylene oxide, could take a week, a U.S. Environmental Protection Agency spokeswoman said. EPA officials said they hope to reopen the Hart building by the end of the year (Goldstein/Nakashima, Washington Post, Dec. 12).
The European-Sudanese Public Affairs Council, a London-based advocacy group, Monday criticized U.S. allegations that Sudan was pursuing a biological weapons program.
The council made the announcement in response to a statement by U.S. Undersecretary of State John Bolton at a U.N. meeting in November (see GSN, Nov. 20). The council said Bolton’s statements were “unsustainable and deeply irresponsible.”
“For its own credibility on this serious issue, the Bush administration cannot allow its reputation with regard to arms control and nonproliferation to be sullied for the sake of cheap propaganda attacks on Sudan,” the council said (U.N. Integrated Regional Information Networks/AllAfrica.com, Dec. 11).
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