On April 13, the UN General Assembly adopts by consensus the International Convention for the Suppression of Acts of Nuclear Terrorism.

The 2005 Nonproliferation Review Conference is held at UN Headquarters in New York May 2-27. The Conference fails to reach any substantive agreement.

On July 18, U.S. President Bush and Indian Prime Minister Singh announce a new strategic partnership, which includes expanding commerce in civil nuclear technology.

On August 1, Iran notifies the IAEA it has decided to resume uranium conversion activities at the Uranium Conversion Facility at Isfahan. Shortly thereafter it removes IAEA seals from the processing line.

The IAEA Board of Governors adopts a resolution on August 11, calling on Iran to re-establish full suspension of enrichment related activities and to reinstate IAEA seals that were removed at Isfahan.

A joint statement released on September 19, in Beijing, at the conclusion of the fourth round of the Six Party Talks, commits parties to a “Statement of Principles” some of which include the denuclearization of the Korean peninsula, and an eventual return by the DPRK to the Nonproliferation Treaty. The preliminary agreement is considered fragile, as North Korea has made repeated declarations that any steps towards dismantlement of its nuclear program is first contingent upon receiving a light water nuclear reactor, something Washington has been reluctant to guarantee.

On September 24, the IAEA Board of Governors adopts a resolution finding Iran in breach and non-compliance in the implementation of IAEA safeguards.

On October 6, the Norwegian Nobel Committee awards the IAEA and Director-General Mohamed Elbaradei, the 2005 Peace Prize.