Commission Chairwoman Allison Macfarlane assumed the post in 2012, after her predecessor Gregory Jaczko announced he would step down amid criticism of his leadership.
The five-member commission seeks to ensure the security and safety of U.S. nuclear reactors and substances. The independent body pursues its mission by awarding and extending licenses for domestic atomic sites and by issuing rules and recommendations for civilian nuclear operations.
Senate Majority Leader Harry Reid (D-Nev.) commended the chairwoman's renomination and said she "is deeply committed to keeping Americans safe and secure from harmful radioactive material and waste."
"I look forward to a swift confirmation of Chairman Macfarlane for a full term at the NRC,” Reid added in a written release. It was unclear when the Senate would act on her nomination.