Reducing AIxBio Risks
Strengthening AI governance to prevent misuse of AI-enabled tools for engineering living systems
AI & Tech
Innovation is reshaping global security.
NTI stays ahead of the curve.
Emerging tech holds promise and risk.
The accelerating pace of global innovation, driven by the democratization of artificial intelligence and dozens of emerging technologies, is redefining global security—opening both unprecedented opportunities and entirely new categories of risks.
As emerging technologies become more accessible, affordable, and convergent, they are empowering broader and more diverse actors —from non-state entities, to startups, to individuals. This shift raises major challenges for nuclear and biological security, which have historically been managed by governments through tightly controlled frameworks.
94% The percentage of PhD-level virologists who were outperformed by AI during an April 2025 benchmarking exercise.
>20,000 AI agents are rapidly becoming embedded in workflows across industries, with current estimates suggesting that tens of thousands of new AI agents are generated per day.
89% In the U.S. nuclear modernization plan, 41 of 46 weapons and related systems examined will receive new or upgraded digital components, with implications for cybersecurity
AI & Emerging Technologies
While the convergence of any of the dozens of emerging technologies can foster horizontal and vertical proliferation of nuclear and biological dangers, the technologies also provide means to see around corners and get ahead of problems. Using these technologies is an important part of managing risks.
Biological & Nuclear
Emerging technologies—especially AI—are rapidly reshaping nuclear and biological security, outpacing state‑centric frameworks built for fewer actors and slower change, eroding long‑standing assumptions about deterrence, arms control, and oversight. To avoid perpetual catch‑up, we must anticipate long‑term technology trends and update our security models accordingly.
Featured Projects
Advancing Nuclear Fail-Safe Reviews
Preventing the accidental or unauthorized use of nuclear weapons
AIxBio Global Forum
Facilitating international governance to reduce biosecurity risks at the convergence of AI and the life sciences.
Nuclear Risks in Outer Space
Advancing Nuclear Risk Reduction in Space
NTI stays ahead of the curve
AI Is Moving Into Nuclear Weapons Systems. Fail-Safe Reviews Are Critical.
The integration of AI into nuclear systems is underway. The guardrails, safety, and security frameworks needed to understand and manage the consequences are not. A new generation of AI-informed nuclear fail-safe reviews is urgently needed in all countries with nuclear weapons.
NTI at 25: Fostering Innovation Through Technology Governance
People Are Trying to Misuse AI. That’s Exactly Why Safeguards Matter.
Resource Collection
AIxBio Horizon Scans
Developing Guardrails for AI Biodesign Tools
Reducing Cyber Risks to Nuclear Weapons: Proposals from a U.S.-Russia Expert Dialogue
