Here we highlight the work of NTI and share knowledge, ideas, and viewpoints addressing the crosscutting challenges our world faces—addressing risks while supporting innovation—to make our world safer.
Bringing Nuclear Risk Reduction to the Digital Generation
Younger generations understand nuclear weapons through digital screens rather than personal experience. The future of nuclear risk reduction hinges on the ability to communicate with and engage young people directly; to educate and mobilize them around nuclear issues.
AI Can Design New Proteins. It’s Time to Build Real Biosecurity Guardrails
As protein design tools and other biological AI models become more capable of designing novel biological components and systems, the mechanisms to prevent misuse have not kept pace.
The convergence of artificial intelligence and the life sciences continues to accelerate. The AIxBio Horizon Scan: Spring 2026 shows that while individual advances may seem incremental, their combined trajectory is significant. Progress is outpacing governance frameworks.
Disney Channel’s The Luck of the Irish reminds us that failing to safeguard a powerful asset—whether a magical lucky coin or advanced emerging technology—can lead to disaster. Strengthening AIxBio governance is about building guardrails to accelerate innovation and safeguards to prevent harm.
The convergence of artificial intelligence and the life sciences is reshaping what’s possible in biology, delivering major advances–ranging from accelerating vaccine discovery to advancing new tools for mitigating the effects of climate change–and new risks. NTI | bio’s AIxBio Horizon Scan looks ahead to where AIxBio capabilities are headed over the coming years.
Managed Access: Preventing AI from Designing Deadly Pathogens
A growing number of the world’s leading experts in health security and the life sciences are warning that unfettered open access to biological data could help AI design dangerous pathogens and are calling for safeguards on high-risk data to prevent misuse of AIxBio tools. Their warnings represent growing momentum behind an idea that NTI has championed: using managed access as a tool to strengthen biosecurity and safeguard rapidly advancing AIxBio capabilities.
Why Responsible AIxBio Innovation Must Be on New Delhi’s Agenda
Some of the world’s largest AI companies—Google DeepMind, OpenAI, and Anthropic—have warned that their models could be misused to cause harm with biology. The India AI Impact Summit is a critical moment for policymakers, scientists, developers, and biosecurity experts to work together on responsible governance that reduces AIxBio risks.
How the U.S. Maintains Its Nuclear Arsenal—Without Explosive Testing
The U.S. ended explosive nuclear testing in the 1990s, but that does not mean we are unprepared. In its place, the U.S. uses a science-based program that checks the health of the stockpile continuously and reports out every year to the President.
Unlike past technological disruptions to global security which were driven by governments, market forces and business dominate today’s global innovation space. This includes working not only with thought leaders, but the doers that affect change. The latest FutureSafe Innovation Forum welcomed Dr. Kimberly Budil, Director of Lawrence Livermore National Laboratory, to discuss the future of national security science.
Innovation requires security, and security requires innovation. Congress needs to act decisively to ensure U.S. leadership in biotechnology is paired with governance that keeps its development secure.