Here we highlight the work of NTI and share knowledge, ideas, and viewpoints addressing the crosscutting challenges our world faces—addressing risks while supporting innovation—to make our world safer.
Angela Guo is a high school student from Hong Kong currently studying at Phillips Academy Andover. She has spent the past year researching the impacts of nuclear testing on the Marshall Islands and recently published her first book, “At the Tide’s Mercy: Voices from the Marshallese Exodus”.
Rethinking Insurance and Legal Responsibility for AI-Enabled Biology
As AI expands what is possible in biology, it’s past time the biosecurity, insurance, and legal communities came together to examine what these developments mean for preventing harm and assigning responsibility if it occurs.
Innovation Enables Responsibility: Watermarking to Strengthen DNA Synthesis Screening
The development of SynthID Bio by a major frontier AI lab is an important reminder that responsible development and cutting-edge progress are not mutually exclusive.
Trump-Xi Summit: Perception, Not Capability, May Drive AI-Bioweapons Risks
The Trump and Xi summit today may offer an opportunity to begin filling the leadership vacuum on AI advances, especially with respect to bioweapons. If the reports from AI companies are correct, it’s imperative that Presidents Trump and Xi start this work now.
AI Is Moving Into Nuclear Weapons Systems. Fail-Safe Reviews Are Critical.
The integration of AI into nuclear systems is underway. The guardrails, safety, and security frameworks needed to understand and manage the consequences are not. A new generation of AI-informed nuclear fail-safe reviews is urgently needed in all countries with nuclear weapons.
NTI at 25: Fostering Innovation Through Technology Governance
As NTI celebrates 25 years of impact, we remain committed to reducing the risks of accidental release and deliberate misuse of life science innovations, strengthening global biosecurity, and guiding efforts to govern emerging technologies.
People Are Trying to Misuse AI. That’s Exactly Why Safeguards Matter.
The policy challenge ahead is ensuring that safeguards, governance frameworks, and security practices continue to responsibly scale alongside the technology. If they do, society can capture AI's enormous benefits while keeping emerging risks firmly under control.
AI Can Design New Proteins. It’s Time to Build Real Biosecurity Guardrails
As protein design tools and other biological AI models become more capable of designing novel biological components and systems, the mechanisms to prevent misuse have not kept pace.
The convergence of artificial intelligence and the life sciences continues to accelerate. The AIxBio Horizon Scan: Spring 2026 shows that while individual advances may seem incremental, their combined trajectory is significant. Progress is outpacing governance frameworks.
Disney Channel’s The Luck of the Irish reminds us that failing to safeguard a powerful asset—whether a magical lucky coin or advanced emerging technology—can lead to disaster. Strengthening AIxBio governance is about building guardrails to accelerate innovation and safeguards to prevent harm.