Programs & Projects

Global Biological Policy & Programs (NTI | bio)

About

Biological threats – whether natural, accidental or deliberate — can kill millions, cost billions, and create political and economic instability in individual countries and around the world. The risks and consequences of a global catastrophic biological event can be magnified by weak global health security, increasing urbanization and travel, growing terrorist interest in weapons of mass destruction, and rapid advances in technology that enable newly developed or manipulated pathogens with pandemic potential.

To reduce these risks and strengthen biosecurity, NTI | bio works with governments, industry, academia, international organizations and NGOs to foster multilateral dialogue, identify weaknesses, and promote systemic change to improve biotechnology governance and national health security capacities.

NTI offers solutions through a range of projects. Among them:

  • Global Health Security Index: Launched in 2019, the GHS Index is the first comprehensive assessment of the health security capacities of 195 countries. The second edition, now in development, will be released in December.
  • Global Biological Catastrophic Risks: NTI | bio’s multi-faceted work in this area includes building a stronger case for decision-makers to prioritize action to counter catastrophic biological risks; establishing new forums focused on preventing the development and use of biological weapons by powerful actors; strengthening the Biological Weapons Convention; and developing innovative solutions for early detection and rapid response.
  • Global Biosecurity Dialogue: To identify way to advance international biosecurity — and measure those advances — NTI | bio brings together senior officials from ministries of foreign affairs, health, defense, agriculture and other relevant sectors to build cross-border collaboration; increase the number of countries providing national, regional, or global financial and technical support to strengthen biosecurity; and promote new actions and investments among senior officials to mitigate emerging biological risks.

Projects

Africa Health Security Index

Africa Health Security Index

Improving epidemic and pandemic preparedness and strengthening biosecurity in Africa.

AIxBio Global Forum

AIxBio Global Forum

Facilitating international governance to reduce biosecurity risks at the convergence of AI and the life sciences.

Biosecurity Dialogues

Biosecurity Dialogues

Reducing the risks of biological misuse and enhancing global security

Biosecurity Innovation and Risk Reduction Initiative

Biosecurity Innovation and Risk Reduction Initiative

Advances in biotechnology outpace national governments’ ability to provide needed oversight to prevent accidents or deliberate misuse of dangerous biological agents.

Global Health Security Index

Global Health Security Index

An assessment and benchmarking of health security and related capabilities across 195 countries.

Reducing AIxBio Risks

Reducing AIxBio Risks

Strengthening AI governance to prevent misuse of AI-enabled tools for engineering living systems

News & Analysis

NTI | bio Engages Global Leaders at GHS2026 in Kuala Lumpur

News

NTI | bio Engages Global Leaders at GHS2026 in Kuala Lumpur

NTI | bio experts will take part in several GHS2026 sessions, including a preview of findings from the forthcoming Africa Health Security (AHS) Index and a timely discussion on strengthening health security partnerships amid declining resources.


AIxBio Horizon Scan: Spring 2026

Paper

AIxBio Horizon Scan: Spring 2026

Since the AIxBio Horizon Scan Winter 2025-2026 published in March 2026, there has been steady, incremental progress across AI-enabled biological tools. Protein design tools have continued to improve, agentic coding tools have matured in ways that lower barriers to computational biology, and commercial AI companies are making significant investments in the life sciences.



Applications Open: Strengthening Biosecurity & Pandemic Preparedness Through Intergenerational Dialogue

News

Applications Open: Strengthening Biosecurity & Pandemic Preparedness Through Intergenerational Dialogue

As breakthroughs in artificial intelligence and biotechnology outpace global governance, the Nuclear Threat Initiative (NTI) and The Elders are launching a new intergenerational initiative to generate the ideas and leadership needed for a safer future against biological threats.



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